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Agricultural by-products of Capsicum annuum, including leaves and stems, are largely discarded despite being rich sources of bioactive compounds such as polyphenols and flavonoids. This study aims to investigate the potential of pepper by-product extracts as novel agents for improving blood circulation and preventing cardiovascular diseases.

The research focuses on elucidating the mechanisms by which these extracts regulate platelet activation, thrombus formation, endothelial function, oxidative stress, and inflammatory responses. Furthermore, their applicability as functional food ingredients and natural therapeutics for vascular health will be evaluated. The study is expected to provide scientific evidence for the valorization of agricultural waste and the development of high-value natural products for cardiovascular health promotion.

[Brief Introduction of Speaker]

I am a Principal Researcher at the Korea Institute of Oriental Medicine (KIOM). His research focuses on platelet biology, thrombosis, vascular inflammation, and the development of natural products for cardiovascular health. He has conducted extensive studies on the discovery of bioactive natural compounds and the elucidation of their pharmacological mechanisms in blood circulation improvement and cardiovascular disease prevention.

Recently, his research has expanded to AI-assisted natural product discovery, organoid-based disease models, and human-mimetic systems for translational biomedical research. He is actively involved in the development of functional foods and natural-product-based therapeutics.​ 

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Efficacy Evaluation and Preliminary Clinical Study for the Development of a Health Functional Food Based on Standardized Black Ginseng Extract for Bronchial Health Improvement

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The research interests of Dr. Ryu are on the isolation, characterization and biological evaluation of natural products of higher plant origin, and he has worked in particular on compounds with potential chronic inflammatory diseases and metabolic diseases, in addition to the scientific study of botanical dietary supplements.​ 

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▷ This technology converts Schisandra pomace, an agricultural by-product, into a high-value functional material through a solid-state fermentation process, and develops an extract containing bioactive compounds that may help improve sleep quality.

▷ Based on the functional evaluation, standardization, and formulation technology of solid-state fermented Schisandra pomace extract, this technology presents its potential commercialization as a health functional food ingredient and sleep-care product.

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(Career History)

• 1996.03.02. ~ 2000.08.26. B.S. in Chemistry, Pusan National University

• 2001.03.02. ~ 2007.02.14. Ph.D. in Chemistry, Pohang University of Science and Technology (POSTECH)

Major: Bioinorganic Materials Chemistry

• 2007.01.16. ~ 2008.04.30. Postdoctoral Researcher, Pohang University of Science and Technology (POSTECH)

• 2008.05.01. ~ 2010.06.30. Postdoctoral Researcher, Max Planck Institute, Germany

• 2010.04.19. ~ 2012.09.30. Senior Researcher, Nanogea, Inc., USA

• 2015.11.01. ~ 2019.10.31. Visiting Professor, School of Chemical Engineering and Polymer Engineering, Sungkyunkwan University

• 2024.03.01. ~ 2025.12.31. Adjunct Professor, Department of Chemical Engineering, Kyungsung University

(Awards and Honors)

• Prime Minister’s Commendation, 2025

• Academic Award, Korean Adhesion and Interface Society, 2024

• Minister’s Commendation, Ministry of Trade, Industry and Energy, 2021

• Chairperson’s Award, National Research Council of Science & Technology, 2021

• KRICT Achievement Award, 2021 and 2025

(Major Research Areas and Expertise)

• Research and development in precision chemical materials and functional materials

• Development and application of interface and surface control materials

• Research, development, and application of industrially applicable materials

• Development of natural product-based and bio-based functional materials

• Expertise in technology transfer, patent acquisition, and industrialization of • R&D outcomes

Experience in planning and conducting national R&D projects based on industry–academia–research collaboration​ 

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Development of Health Functional Foods for Sleep Improvement Using Glehnia littoralis Extract

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1. Head, Functional Platform Research Group, Korea Food Research Institute

2. Professor, Food Biotechnology, UST​ 

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Against the backdrop of recent health and wellness trends, the Japanese health food market continues to evolve constantly. This development is driven by the diversification of products addressing a wide range of demands from seniors to younger generations, as well as the solid establishment of the "Foods with Function Claims" system, which allows products to display specific health benefits.

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After graduating from university, they began their career in 1998 at a major Japanese food manufacturer before joining Yano Research Institute in 2003. They specialize in the overall food market, with a particular focus on the health food and processed food industries. Currently serving as the leader of the Food Group, they oversee the department's entire domain.

They have an extensive track record in feasibility studies for new business ventures, market entry research for foreign companies entering Japan, industry development support for local governments, and market expansion assistance for foreign embassies in Japan.​

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CEO of CAREGEN (2001~) - Post Doc. Northwestern University, Hormonal & Dietary gene modulation in Breast cancer cells (2001) 

Ph.D. Animal Science, Cornell University, BRCA Research in Bovine mammary gland (2000) 

M.S. Biochemistry, University of Texas at San Antonio (1996) 

B.S. Genetic Engineering, SungGyunGwan University, Korea (1994)​ 

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Lipid excipients have a proven history of enhancing bioavailability of drugs through the improvement of solubility, permeability, and absorption. Being often liquid at room temperature, they are mainly formulated in liquid forms. That said, oral solid dosage forms such as tablets could benefit from the advantages of lipid excipients. This presentation will highlight different processes to incorporate lipid excipients in oral tablets or powders.

Key topics will include:

- Benefits of lipid excipients for bio-enhancement

- Market references

- Case studies highlighting formulation strategies and associated manufacturing processes.

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Hongyi holds a Bachelor’s degree in Pharmacy (1st class) and PhD in Pharmaceutical Technology from the National University of Singapore (NUS). During his research, he investigated on solid oral dosage formulations at GEA-NUS laboratory under the supervision of A/Prof Chan Lai Wah and A/Prof Paul Heng.

Prior to joining Gattefossé, Hongyi was a senior technical engineer at Merck Sharpe and Dohme (MSD) and formulation scientist at Clinuvel Pharmaceuticals.

At Gattefossé since 2022, Hongyi is responsible for technical marketing in the pharmaceutical division for the Asia Pacific region, covering oral, topical and rectal drug delivery. Additionally, he is responsible for sales in Thailand, Malaysia, Australia and New Zealand. Outside of work, Hongyi is a keen volleyball player and enjoys travelling.​